SELENOP Antilichaam - N-terminalgebied: FITC (ARP56299_P050-FITC)

Selenoprotein P

SeP, SELP, SEPP, SEPP1

6414

P49908

NP_001087195

Human, Horse

The immunogen is a synthetic peptide directed towards the N terminal region of human SEPP1

This gene encodes a selenoprotein that is predominantly expressed in the liver and secreted into the plasma. This selenoprotein is unique in that it contains multiple selenocysteine (Sec) residues per polypeptide (10 in human), and accounts for most of the selenium in plasma. It has been implicated as an extracellular antioxidant, and in the transport of selenium to extra-hepatic tissues via apolipoprotein E receptor-2 (apoER2) . Mice lacking this gene exhibit neurological dysfunction, suggesting its importance in normal brain function. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. The mRNA for this selenoprotein contains two SECIS elements. Alternatively spliced transcript variants have been found for this gene.

EP300; MEOX2; THRA; EGFR

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

SEPP1 is supported by BioGPS gene expression data to be expressed in HEK293T

0.5 mg/ml

Horse: 85%; Human: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

46kDa

Peters, U., (2008) Cancer Epidemiol. Biomarkers Prev. 17 (5), 1144-1154

Wet Ice

411

SELENOP

SELENOP

Rabbit

Selenoprotein P

NM_001093726

LGLALALCLLPSGGTESQDQSSLCKQPPAWSIRDQDPMLNSNGSVTVVAL