SETD2 Antilichaam - N-terminalgebied : HRP (ARP47617_T100-HRP)

SET domain containing 2

LLS, HYPB, SET2, HIF-1, HIP-1, KMT3A, HBP231, HSPC069, p231HBP

29072

Q9BYW2

AAH72440

Human, Mouse, Rat, Dog, Horse

The immunogen is a synthetic peptide directed towards the N terminal region of human SETD2

Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. SETD2 is a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs.

CLK2; SOX2; CBX8; HCVgp1; SIAH2; SMAD3; CIC; ATXN1; ELAVL1; UBC; SETD2; HIST1H3A; POLR2A; TP53; IWS1; HTT

HRP: Horseradish Peroxidase

Polyclonal Antibody

IHC, WB

SETD2 is strongly supported by BioGPS gene expression data to be expressed in HepG2

0.5 mg/ml

Dog: 86%; Horse: 86%; Human: 100%; Mouse: 83%; Rat: 85%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

97kDa

Wet Ice

891

SETD2

SETD2

Rabbit

Histone-lysine N-methyltransferase SETD2

NM_014159

SDEDSVRTSSSQRSHDLKFSASIEKERDFKKSSAPLKSEDLGKPSRSKTD