SLC22A18 Antilichaam - N-terminalgebied : HRP (ARP43825 P050-HRP)

Solute carrier family 22, member 18

HET, ITM, BWR1A, IMPT1, TSSC5, ORCTL2, BWSCR1A, SLC22A1L, p45-BWR1A

5002

Q96BI1

NP_002546

Human, Mouse, Rat, Cow, Guinea Pig, Horse

The immunogen is a synthetic peptide directed towards the N terminal region of human SLC22A18

This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region as well as the transport of chloroquine- and quinidine-related compounds in the kidney.This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region as well as the transport of chloroquine- and quinidine-related compounds in the kidney. Two alternative transcripts encoding the same isoform have been described.

RNF167; UBC

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

SLC22A18 is supported by BioGPS gene expression data to be expressed in HepG2

0.5 mg/ml

Cow: 86%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 86%; Rat: 79%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

45kDa

Gallagher, E., (2006) Genomics 88 (1), 12-17

Wet Ice

424

SLC22A18

SLC22A18

Rabbit

Solute carrier family 22 member 18

NM_002555

AASSPALPGVYLLFASRLPGALMHTLPAAQMVITDLSAPEERPAALGRLG