SOX18 Antilichaam - middengebied HRP (ARP33056-P050-HRP)

SRY (sex determining region Y) -box 18

HLTS, HLTRS

54345

P35713

NP_060889

Human, Mouse, Rat, Cow, Guinea Pig

The immunogen is a synthetic peptide directed towards the middle region of human SOX18

SOX18 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. This protein plays a role in hair, blood vessel, and lymphatic vessel development. Mutations in this gene have been associated with recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia.

GKAP1; MECP2; MEF2C; HMGB1

HRP: Horseradish Peroxidase

Polyclonal Antibody

IF, WB, IHC

Affinity Purified

0.5 mg/ml

Cow: 86%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rat: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

41kDa

Spataro, V., et al., (2005) Arterioscler. Thromb. Vasc. Biol. 25 (11), 2398-2403

Wet Ice

384

SOX18

SOX18

Rabbit

Transcription factor SOX-18

NM_018419

RTAPPAAPLAGLYYGTLGTPGPYPGPLSPPPEAPPLESAEPLGPAADLWA