SPACA1 Antilichaam - N-terminalgebied: HRP (ARP49984_P050-HRP)

Sperm acrosome associated 1

SAMP32

81833

Q9HBV2

NP_112222

Human

The immunogen is a synthetic peptide directed towards the N terminal region of human SPACA1

The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from infertile males. Furthermore, antibodies generated against the recombinant protein block in vitro fertilization. This protein localizes to the acrosomal membrane of spermatids and mature spermatozoa where it is thought to play a role in acrosomal morphogenesis and in sperm-egg binding and fusion, respectively.

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

SPACA1 is supported by BioGPS gene expression data to be expressed in NCIH226

0.5 mg/ml

Human: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

32kDa

Wet Ice

294

SPACA1

SPACA1

Rabbit

Sperm acrosome membrane-associated protein 1

NM_030960

TENNDSETAENYAPPETEDVSNRNVVKEVEFGMCTVTCGIGVREVILTNG