STEAP3 Antilichaam - C-terminalgebied: HRP (ARP43515 P050-HRP)

STEAP family member 3, metalloreductase

STMP3, TSAP6, pHyde, AHMIO2, dudlin-2, dudulin-2

55240

A8K6E3

NP_878919

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the C terminal region of human STEAP3

AS an endosomal ferrireductase, STEAP3 is required for efficient transferrin-dependent iron uptake in erythroid cells. It participates in erythroid iron homeostasis by reducing Fe (3+) to Fe (2+) and can also reduce of Cu (2+) to Cu (1+), suggesting that it participates in copper homeostasis. STEAP3 uses NAD (+) as acceptor (By similarity) . It may play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. STEAP3 is indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCT.

UBC; SETD7; BAD; TPT1; BNIP3L; PKMYT1

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 93%; Dog: 86%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 93%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

56kDa

Sendamarai, A.K., (2008) Proc. Natl. Acad. Sci. U.S.A. 105 (21), 7410-7415

Wet Ice

498

STEAP3

STEAP3

Rabbit

Metalloreductase STEAP3

NM_182915

VALVLSTLHTLTYGWTRAFEESRYKFYLPPTFTLTLLVPCVVILAKALFL