STK11 Antilichaam - N-terminaal gebied: Biotine (ARP41743_T100-Biotine)

Serine/threonine kinase 11

PJS, LKB1, hLKB1

6794

Q15831

NP_000446

Human, Mouse, Rat, Dog, Guinea Pig, Horse, Zebrafish

The immunogen is a synthetic peptide directed towards the N terminal region of human STK11

STK11is a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in its gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms.This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

SPDEF; SIRT1; PRKAA1; ETV4; CDC37; HSP90AA1; TP63; Eif2b1; Ap2m1; SNRK; APP; TNIP2; SIK1; STRADA; STUB1; UBE2D2; MARK2; GSK3B; STRADB; CAB39; KIF23; USP11; SMARCC1; SMARCA4; LIMS1; HSPA1A; FKBP5; RPAP3; MARK4; UBC; CAB39L; WDR48; RPS6KB1; MOB4; MARK1; RPS

Biotin

Polyclonal Antibody

IHC, WB

STK11 is supported by BioGPS gene expression data to be expressed in Jurkat

0.5 mg/ml

Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

48kDa

Xie, Z., (2006) J. Biol. Chem. 281 (10), 6366-6375

Wet Ice

433

STK11

STK11

Rabbit

Serine/threonine-protein kinase STK11

NM_000455

TLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHKNVIQLVDVLYNE