SWAP70 Antilichaam - N-terminalgebied: FITC (ARP46214_T100-FITC)

SWAP switching B-cell complex 70kDa subunit

HSPC321, SWAP-70

23075

Q9UH65

NP_055870

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the N terminal region of human SWAP70

Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. SWAP70 also mediates signaling of membrane ruffling. It regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4) -bisphosphate production and cell protrusion.

ZBTB5; RAPGEF4; UBC; CORO1B; ASUN; OTUD6B; JMJD6; GANAB; PACSIN2; FAF1; PAICS; FARSB; ZRANB2; RANBP3; CUL1; SUPT5H; SET; PPP2R5C; PLOD2; OSBP; GART; XRCC6; CRMP1; ATP6V1B2; C18orf8; CELSR3; IGHG1; PARP1; NPM1; NCL

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

69kDa

Liu, J., (2007) J. Histochem. Cytochem. 55 (7), 701-708

Wet Ice

585

SWAP70

SWAP70

Rabbit

Switch-associated protein 70

NM_015055

ALEEHFRDDDEGPVSNQGYMPYLNRFILEKVQDNFDKIEFNRMCWTLCVK