TAF11 Antilichaam - N-terminalgebied: FITC (ARP32136 P050-FITC)

TAF11 RNA polymerase II, TATA box binding protein (TBP) -associated factor, 28kDa

TAF2I, PRO2134, TAFII28, MGC:15243

6882

Q15544

NP_005634

Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the N terminal region of human TAF11

TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. TAF11 is a small subunit of TFIID that is present in all TFIID complexes and interacts with TBP. This subunit also interacts with another small subunit, TAF13, to form a heterodimer with a structure similar to the histone core structure.Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit of TFIID that is present in all TFIID complexes and interacts with TBP. This subunit also interacts with another small subunit, TAF13, to form a heterodimer with a structure similar to the histone core structure.

APPBP2; MED26; HIST3H3; APP; TBP; ELAVL1; POLR2A; ACTB; TAF8; VDR; THRA; NFYC; NFYB; NFYA; LZTR1; TAF9; TAF12; TAF10; TAF5; TAF13; TAF6; TAF4; TAF7; TAF2; CPSF1; TRIM24; TAF1; RXRB; RXRA; RELA; TAF15; GTF2F1; GTF2E1; GTF2B

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 92%; Guinea Pig: 100%; Horse: 92%; Human: 100%; Mouse: 83%; Rabbit: 92%; Rat: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

23kDa

Guermah, M., (2003) Mol. Cell 12 (4), 991-1001

Wet Ice

211

TAF11

TAF11

Rabbit

Transcription initiation factor TFIID subunit 11

NM_005643

MDDAHESPSDKGGETGESDETAAVPGDPGATDTDGIPEETDGDADVDLKE

11