
TG101209
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
936091-14-4
C17007-10mg
C-RET
Protein Tyrosine Kinase
CC1=CN=C (N=C1NC2=CC (=CC=C2) S (=O) (=O) NC (C) (C) C) NC3=CC=C (C=C3) N4CCN (CC4) C
C26H35N7O2S
TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM, less potent to Flt3 and RET (c-RET) with IC50 of 25 nM and 17 nM in cell-free assays, ~30-fold selective for JAK2 than JAK3, sensitive to JAK2V617F and MPLW515L/K mutations.
2 years -80 in solvent
Beschrijving
TG101209 Beschikbaar in 10 mg. Wordt geleverd met droogijs. Bestel eenvoudig online met snelle levering.
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