TUB Antibody - N-terminal regio : HRP (ARP57909_P050-HRP)

Tubby homolog (mouse)

Rd5, RDOB

7275

P50607

NP_003311

Human, Dog, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the N terminal region of human TUB

TUB functions in signal transduction from heterotrimeric G protein-coupled receptors. It could be involved in the hypothalamic regulation of body weight.This gene encodes a member of the Tubby family of bipartite transcription factors. The encoded protein may play a role in obesity and sensorineural degradation. The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis. Two transcript variants encoding distinct isoforms have been identified for this gene.

UBC; SUV420H2; GNAQ; SRC; ABL1; PLCG1; PIK3R1; LCK; JAK2; IRS1; GRB2

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB, IHC

Affinity Purified

0.5 mg/ml

Dog: 83%; Horse: 92%; Human: 100%; Rabbit: 91%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

62kDa

Snieder, H., (2008) Diabetologia 51 (1), 54-61

Wet Ice

561

TUB

TUB

Rabbit

Tubby protein homolog

NM_003320

MGARTPLPSFWVSFFAETGILFPGGTPWPMGSQHSKQHRKPGPLKRGHRR