TUT1 Antilichaam - middengebied: HRP (ARP39567 P050-HRP)

Terminal uridylyl transferase 1, U6 snRNA-specific

PAPD2, RBM21, TENT1, URLC6, TUTase, STARPAP

64852

A8K995

NP_073741

Human

The immunogen is a synthetic peptide directed towards the middle region of human TUT1

TUT1 is a nucleotidyl transferase that functions as both a terminal uridylyltransferase and a nuclear poly (A) polymerase. TUT1 specifically adds and removes nucleotides from the 3' end of small nuclear RNAs and select mRNAs and may function in controlling gene expression and cell proliferation. TUT1 specifically catalyzes uridylylation of U6 snRNA (RNU6; MIM 180692) and is essential for cell proliferation (Trippe et al., 2006 [PubMed 16790842]) .[supplied by OMIM].

HUWE1; IL32; SUMO2; TIMELESS; PIN1; FBXO6; SOX2; CPSF3; CPSF1; HMOX1; UBC; YWHAQ; MEPCE; USP15; SART3; PRPF4; USP4

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Human: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

94kDa

Gonzales, M.L., (2008) J. Biol. Chem. 283 (18), 12665-12673

Wet Ice

874

TUT1

TUT1

Rabbit

Speckle targeted PIP5K1A-regulated poly (A) polymerase

NM_022830

EGAGGGAGTRAGWLATEAQVTQELKGLSGGEERPETEPLLSFVASVSPAD