UBE2I Antilichaam - N-terminaal gebied: Biotine (ARP43021 T100-Biotine)

Ubiquitin-conjugating enzyme E2I

P18, UBC9, C358B7.1

7329

P63279

NP_003336

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the N terminal region of human UBE2I

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2I is a member of the E2 ubiquitin-conjugating enzyme family.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Four alternatively spliced transcript variants encoding the same protein have been found for this gene.

TRIM21; SP100; SUMO2; RANGAP1; PTEN; LMO2; PIAS2; TRIM23; PARP1; PIAS4; UBXN1; USP25; SETBP1; SIRT1; PUF60; HMGA1; GOLGA2; FHL3; ELK1; DES; DAXX; CREBBP; CLK2; RCBTB2; CEBPD; CBS; CAPN2; PPARGC1A; RFPL3; TRIM38; IKZF1; RNF40; XBP1; KRT19; HNRNPC; ZBTB8A

Biotin

Polyclonal Antibody

WB

There is BioGPS gene expression data showing that UBE2I is expressed in Jurkat

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

17kDa

Zhu, S., (2006) Exp. Cell Res. 312 (7), 1042-1049

Wet Ice

158

UBE2I

UBE2I

Rabbit

SUMO-conjugating enzyme UBC9

NM_003345

MSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKG