UBE2J1 Antilichaam - N-terminalgebied: FITC (ARP43206 T100-FITC)

Ubiquitin-conjugating enzyme E2, J1, U

UBC6, UBC6E, Ubc6p, CGI-76, NCUBE1, HSPC153, HSPC205, NCUBE-1, HSU93243

51465

Q9Y385

NP_057105

Human, Mouse, Rat, Guinea Pig, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the N terminal region of human UBE2J1

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2J1 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum (ER) and may contribute to quality control ER-associated degradation by the ubiquitin-proteasome system.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum (ER) and may contribute to quality control ER-associated degradation by the ubiquitin-proteasome system.

UBC; UBA1; MAPKAPK2; OS9; RNF5; PARK2; DIO2; SOX6; TP53; AUP1; ASNA1; DERL3; DERL1; YOD1; DERL2; FAF2; VCP; SEL1L; ELAVL1; HLA-A; BIRC2; LRSAM1; TRIM63; SYVN1; TOPORS; PJA2; RNF2; TRIM27; BRCA1; BIRC3

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

IHC, WB

UBE2J1 is supported by BioGPS gene expression data to be expressed in Jurkat

0.5 mg/ml

Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

35kDa

Lenk, U., J. Cell. Sci. 115 (PT 14), 3007-3014 (2002)

Wet Ice

318

UBE2J1

UBE2J1

Rabbit

Ubiquitin-conjugating enzyme E2 J1

NM_016021

METRYNLKSPAVKRLMKEAAELKDPTDHYHAQPLEDNLFEWHFTVRGPPD