UBTF-antilichaam - C-terminalgebied: FITC (ARP39068_P050-FITC)

Upstream binding transcription factor

UBF, UBF1, UBF2, UBF-1, CONDBA, NOR-90

7343

P17480

XP_006722124

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Yeast, Zebrafish

The immunogen is a synthetic peptide directed towards the C-terminal region of Human UBF1

This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11.

UBC; MDM2; RNF2; Dlg4; ESR1; CDK4; CDK2; CCNE1; CCND1; WDR70; YEATS4; RB1; GRK5; KAT5; SIRT7; POLR1A; MYBBP1A; HDAC1; RUNX2; SUMO2; SMARCA5; MAPK3; MAPK1; SUMO1; PIK3CA; IRS1; TAF1D; tat; MCRS1; TLE1; ACTN4; POLR1E; CHGB; SMURF1; TCOF1; MAD1L1; ZMYM2; SER

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 86%; Pig: 86%; Rabbit: 93%; Rat: 93%; Yeast: 86%; Zebrafish: 79%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

84kDa

Wet Ice

764

UBTF

UBTF

Rabbit

Nucleolar transcription factor 1

SEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSS