UGT1A5 Antilichaam - N-terminaal gebied: Biotine (ARP49439 P050-Biotine)

UDP glucuronosyltransferase 1 family, polypeptide A5

UDPGT, UGT1E, UDPGT 1-5

54579

P35504

NP_061951

Human, Rat

The immunogen is a synthetic peptide directed towards the N terminal region of human UGT1A5

This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter.

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Human: 100%; Rat: 83%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

57kDa

Wet Ice

534

UGT1A5

UGT1A5

Rabbit

UDP-glucuronosyltransferase 1-5

NM_019078

EENFFTLTTYAISWTQDEFDRLLLGHTQSFFETEHLLMKFSRRMAIMNNM