WBP11 Antilichaam - N-terminalgebied: HRP (ARP46241_P050-HRP)

WW domain binding protein 11

BUG13, FAP90, NPWBP, SIPP1, VCTRL, CFAP90, VCTERL, WBP-11, PPP1R165

51729

Q9Y2W2

NP_057396

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the N terminal region of human WBP11

WBP11 is a nuclear protein, which colocalizes with mRNA splicing factors and intermediate filament-containing perinuclear networks. WBP11has 95% amino acid sequence identity to the mouse Wbp11 protein. It contains two proline-rich regions that bind to the WW domain of Npw38, a nuclear protein, and thus this protein is also called Npw38-binding protein NpwBP. The Npw38-NpwBP complex may function as a component of an mRNA factory in the nucleus.This gene encodes a nuclear protein, which colocalizes with mRNA splicing factors and intermediate filament-containing perinuclear networks. This protein has 95% amino acid sequence identity to the mouse Wbp11 protein. It contains two proline-rich regions that bind to the WW domain of Npw38, a nuclear protein, and thus this protein is also called Npw38-binding protein NpwBP. The Npw38-NpwBP complex may function as a component of an mRNA factory in the nucleus.

TESC; TRAF4; GRB2; FYN; UBC; BMI1; APBB1; WBP4; HECW2; DDX17; RBM5; PPP1CA; DDX5; CTNNBL1; PPP1CC; UPF3B; ZC3H13; CPSF6; SNRPB2; PQBP1; CD2BP2; SF3A2; ITSN1; RTN4IP1; PPP1CB; GIGYF2; MCRS1; PRPF40A; C5orf22; NCK2; TRIP10; NCF1; VIM; SRC; PIK3R1; RUNX1T1

HRP: Horseradish Peroxidase

Polyclonal Antibody

IHC, IP, WB

Affinity Purified

WBP11 is strongly supported by BioGPS gene expression data to be expressed in HeLa, Jurkat

0.5 mg/ml

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

70kDa

Olsen, J.V., (2006) Cell 127 (3), 635-648

Wet Ice

641

WBP11

WBP11

Rabbit

WW domain-binding protein 11

NM_016312

GRRSTSSTKSGKFMNPTDQARKEARKRELKKNKKQRMMVRAAVLKMKDPK