WWOX Antilichaam - N-terminalgebied: HRP (ARP61393 P050-HRP)

FOR, WOX1, DEE28, EIEE28, FRA16D, SCAR12, HHCMA56, PRO0128, SDR41C1, D16S432E

51741

Q9NZC7-2

Human

The immunogen is a synthetic peptide directed towards the N-terminal region of Human WWOX

This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. This gene spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein. Alternative splicing results in multiple transcript variants.

ITCH; TRIM28; HUWE1; UBC; ATM; RPRD2; CYFIP1; SPG20; SNRNP200; ACIN1; SLC4A1AP; DHX30; SCAF8; XRN2; GABARAPL2; SEC23IP; HNRNPUL1; DIDO1; CPSF6; SF3B2; SF3A3; SRSF10; USP39; IGF2BP2; IGF2BP3; IGF2BP1; PAICS; PRPF8; CCT2; CCT7; NOP56; DDX17; SEC23A; BAIAP2

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

39kDa

Wet Ice

363

WWOX

WWOX

Rabbit

EKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQVFFVDHINKRTTYLDPR