XBP1 Polyklonale Antilichaam, PE-Cy7 Vervoeging

Transcription factor essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response (UPR) . Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE) . Binds DNA preferably to the CRE-like element 5'-GATGACGTG[TG]N (3) [AT]T-3', and also to some TPA response elements (TRE) . Binds to the HLA DR-alpha promoter. Binds to the Tax-responsive element (TRE) of HTLV-I.

XBP2; TREB5; XBP-1; X-box-binding protein 1; Tax-responsive element-binding protein 5; XBP1

7494

P17861

Cytoplasm, Nucleus, Cell membrane

Human, Mouse, Rat

51-150/261

XBP1

PE-Cy7

KLH conjugated synthetic peptide derived from human XBP-1

WB, FCM

Purified by Protein A.

488nm/780nm

1µg/µl

WB (1:300-5000), FCM (1:20-100)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

XBP-1 antibody will recognize both isoforms, may also interact with chicken

7494

Cow, Chicken