Xylitol-13C5
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Xylitol-13C5 (Xylite-13C5) is the 13C-labeled Xylitol. Xylitol can be classified as a polyol and sugar alcohol, exhibiting inhibitory activity on cancer cell proliferation. It induces autophagy (Autophagy) and cell death in A549 cells by activating the autophagy signaling pathway, as evidenced by the increased expression of LC3-II and Atg5-Atg12 upon Xylitol treatment. Additionally, Xylitol inhibits acetaldehyde production by Candida species, thereby reducing their carcinogenic potential. In vivo, Xylitol induces alterations in the gut microbiota of mice, which may enhance cholesterol accumulation and upregulate hepatic ChREBP, while also slowing tumor growth in the B16F10 melanoma C57BL/6 mouse model[1][2][3][4].
Xylite-13C5
12352211
Atg7; Atg8/LC3; Autophagy; Bacterial; Endogenous Metabolite; Isotope-Labeled Compounds
Anti-infection; Autophagy; Metabolic Enzyme/Protease; Others
Cancer
O[13CH2][13C@H](O)[13C@@H](O)[13C@H](O)[13CH2]O
13C5H12O5
157.11
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W768347/
Isotope-Labeled Compounds
No Development Reported
Beschrijving
Xylitol-13C5 (Xylite-13C5) is the 13C-labeled Xylitol. Xylitol can be classified as a polyol and sugar alcohol, exhibiting inhibitory activity on cancer cell pr
Specificaties
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