YY1 Antilichaam - N-terminalgebied: HRP (ARP38301_P050-HRP)

YY1 transcription factor

DELTA, NF-E1, UCRBP, GADEVS, INO80S, YIN-YANG-1

7528

P25490

NP_003394

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Sheep, Zebrafish

The immunogen is a synthetic peptide directed towards the N terminal region of human YY1

YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1.YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1.

HDAC1; SMURF2; UBC; SHFM1; RNF2; BMI1; SUZ12; RYBP; GABPB1; GABPA; PCGF2; RING1; EP300; LAMC2; SPRY1; SLC39A7; NR1H2; TESK1; RAF1; NFKB1; GRN; CRKL; ARRB1; SP1; WDHD1; ZNF24; NHP2L1; NCL; ZNF830; APP; ZNF638; EED; SMAD3; SMAD2; EZH2; SUMO1; SUMO3; INO80E

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

There is BioGPS gene expression data showing that YY1 is expressed in Jurkat

0.5 mg/ml

Cow: 100%; Dog: 100%; Horse: 91%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%; Sheep: 93%; Zebrafish: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

45kDa

Mai, R.T., et al., (2006) Oncogene 25 (3), 448-462

Wet Ice

414

YY1

YY1

Rabbit

Transcriptional repressor protein YY1

NM_003403

MASGDTLYIATDGSEMPAEIVELHEIEVETIPVETIETTVVGEEEEEDDD