
CDK8/CycC Recombinant humaan actief eiwit Kinase
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
CDK8 modulates the transcriptional output from distinct transcription factors involved in oncogenic control, including the Wnt/β-catenin pathway, Notch, p53, and transforming growth factor β. Abnormal activity ofCDK8 along with its partner protein cyclin C (CycC) is a common feature of many diseases including colorectal cancer. CDK8/CycC Recombinant Human Active Protein Kinase can be used to study the function of CDK8/CycC[1].
12352211
CDK
Cell Cycle/DNA Damage
Cancer
[CDK8/CycCRecombinantHumanActiveProteinKinase]
[1]Cholko T, et al. A molecular dynamics investigation of CDK8/CycC and ligand binding: conformational flexibility and implication in drug discovery. J Comput Aided Mol Des. 2018 Jun;32 (6) :671-685.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-E70690/
Enzyme
No Development Reported
Beschrijving
CDK8 modulates the transcriptional output from distinct transcription factors involved in oncogenic control, including the Wnt/β-catenin pathway, Notch, p53, an
Specificaties
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