CDK8/CycC Recombinant humaan actief eiwit Kinase
Gecertificeerd

CDK8/CycC Recombinant humaan actief eiwit Kinase

Catalog #: HY-E70690
Maat: 1 Each

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

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Gratis verzending vanaf €100

Technische Specificaties

Description

CDK8 modulates the transcriptional output from distinct transcription factors involved in oncogenic control, including the Wnt/β-catenin pathway, Notch, p53, and transforming growth factor β. Abnormal activity ofCDK8 along with its partner protein cyclin C (CycC) is a common feature of many diseases including colorectal cancer. CDK8/CycC Recombinant Human Active Protein Kinase can be used to study the function of CDK8/CycC[1].

UNSPSC

12352211

Target

CDK

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Smiles

[CDK8/CycCRecombinantHumanActiveProteinKinase]

References & Citations

[1]Cholko T, et al. A molecular dynamics investigation of CDK8/CycC and ligand binding: conformational flexibility and implication in drug discovery. J Comput Aided Mol Des. 2018 Jun;32 (6) :671-685.

Shipping Conditions

Room temperature

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-E70690/

Scientific Category

Enzyme

Clinical Information

No Development Reported

Beschrijving

CDK8 modulates the transcriptional output from distinct transcription factors involved in oncogenic control, including the Wnt/β-catenin pathway, Notch, p53, an

Specificaties

ProductnaamCDK8/CycC Recombinant humaan actief eiwit Kinase
Categorie
Beschikbare grootte1 Each
CatalogusnummerHY-E70690