Sirtratumab vedotin
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Sirtratumab vedotin (ASG15-ME) is an ADC composed of a SLITRK6-specific human gamma 2 antibody (Igγ2) conjugated to a small molecule microtubule disrupting agent, monomethyl auristatin E (MMAE) via a protease-cleavable linker[1].
1824663-83-3
AGS15E; ASG-15ME; 1vcMMAE
12352203
Antibody-Drug Conjugates (ADCs)
Antibody-drug Conjugate/ADC Related
Cancer-programmed cell death
Cancer
96.42
H2O
[Sirtratumabvedotin]
[1]Morrison K, et al. Development of ASG-15ME, a Novel Antibody-Drug Conjugate Targeting SLITRK6, a New Urothelial Cancer Biomarker. Mol Cancer Ther. 2016 Jun;15 (6) :1301-10.
Dry Ice
-80°C, protect from light
http://file.medchemexpress.com/batch_PDF/HY-P99595/Sirtratumab-vedotin-SDS-MedChemExpress.pdf
ADC Related
Phase 1
Beschrijving
Sirtratumab vedotin (ASG15-ME) is an ADC composed of a SLITRK6-specific human gamma 2 antibody (Igγ2) conjugated to a small molecule microtubule disrupting agen
Specificaties
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